The dreaded protozoal diseases caused by a number of Kinetoplastid parasites threaten mankind, as therapeutic tools for the treatment of most parasitic diseases are extremely limited. Development of commercially available vaccines is still far from reality, though research and trial programs continue. This book covers current research into drug therapeutics for the conditions caused by the parasites, which if viewed globally, pose an increasing threat to human health and welfare.UDP-GlcNAc ac specific PI substrate GPI-N-GlcNAc- transferase N- acetylglucosaminyl-phosphatidylinositol (GlcNAc PI) N ... Schematic representation of GPI biosynthetic pathway in Trypanosoma sp. ... 5aquot;36 and secreted glycoconjugates, proteophosphoglycan (PPG)37-38 and secreted acid phosphatase (sAP)39-42 (Fig.
|Title||:||Drug Targets in Kinetoplastid Parasites|
|Author||:||Hemanta K. Majumder|
|Publisher||:||Springer Science & Business Media - 2008-09-15|