qHelps you efficiently master the core concepts you need to know for your courses and USMLE exams. Get a rich understanding of all essential pathology concepts ... Grasp the connections between basic science and clinical medicine with clinicopathologic correlations throughout.q--Provided by publisher.Genetic factors TGF-[51 polymorphisms ofl-antitrypsin deficiency Environmental exposures Tobacco smoke Biomass fuels, others ... Multiple genetic factors control the response to injury after smoking. ... For example, with certain polymorphisms, mesenchymal cell response to TGF-[3 signaling is reduced, which in turn results in inadequate repair of elastin injury caused ... By contrast, patients with fibrosing lung diseases have excessive myofibroblastic or fibroblastic response to injury, anbsp;...
|Title||:||Robbins Basic Pathology|
|Author||:||Vinay Kumar, Abul K. Abbas, Jon C. Aster|
|Publisher||:||Elsevier Health Sciences - 2012|