Role of the Median Preoptic Nucleus in Chronic Blood Pressure Regulation by Angiotensin II.

Role of the Median Preoptic Nucleus in Chronic Blood Pressure Regulation by Angiotensin II.

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The first specific aim was designed to test the hypothesis that the intact MnPO is necessary for the full hypertensive response to chronic intravenous ANG II administration. In this specific aim, rats with electrolytic lesion of the MnPO displayed significantly attenuated hypertensive responses by day 7 through day 10 of ANG II infusion compared to sham lesioned rats. Therefore, we concluded that the MnPO is a crucial component of the central neuronal circuitry mediating chronic ANG II-induced hypertension.... specific aim 1...............27 Figure 4: A schematic diagram illustrating the hypothesis of specific aim 2...............28 Figure 5: A schematic diagram illustrating the hypothesis of specific aim 3...............29 Chapter II: An intact median preoptic nucleusanbsp;...


Title:Role of the Median Preoptic Nucleus in Chronic Blood Pressure Regulation by Angiotensin II.
Author:Trasida Ployngam
Publisher:ProQuest - 2008
ISBN-13:

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