This extensively revised, updated, and expanded second edition of a classic laboratory manual applies new understanding of molecular mechanisms to the rational design and development of vaccines. Here the working researcher will find readily reproducible techniques for the development and production of live attenuated vaccines, and vaccines based on inactivated toxins, peptides, and polysaccharide conjugates.Mekalanos, J. J., Swartz D. J., Pearson, G. D., Harford, N., Groyne, F., and de Wilde, M. (1983) Cholera toxin genes: nucleotide sequence, deletion analysis ... A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp.
|Author||:||Martin P. Cranage|
|Publisher||:||Springer Science & Business Media - 2003-01-01|